Recombinant CD20 Antibody [RMC20-1]
Product Specifications
Background
CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells. It has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. It has been shown that CD20 plays a role in the microenvironmental interactions of B cells. [Wiki]
NCBI Gene ID
931
Swiss Prot
P11836
Host
Rabbit
Reactivity
Human
Immunogen
Full length human CD20 protein was used as the immunogen for this reccombinant CD20 antibody.
Clonality
Recombinant Monoclonal
Clone
RMC20-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein A affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=34-059
Fragment
IgG, kappa
Applications Notes
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
MS4A1
NCBI Official Name
Membrane-spanning 4-domains, subfamily A, member 1
NCBI Organism
Homo sapiens
Other Product Names
B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
Tested Applications
IHC
Physical Properties
Liquid
Curated Selection
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