E-Cadherin Antibody [ECD1-2]

Product Specifications

Background

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. [UniProt]

NCBI Gene ID

999

Swiss Prot

P12830

Host

Mouse

Reactivity

Human

Immunogen

A full length recombinant human protein was used as the immunogen for the E-Cadherin antibody.

Clonality

Monoclonal

Clone

ECD1-2

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG1, kappa

Specificity

Not suitable for Mouse, Rat sample testing

Symbol

CDH1

NCBI Official Name

Cadherin 1, type 1, E-cadherin (epithelial)

NCBI Organism

Homo sapiens

Other Product Names

Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO

Tested Applications

IF, WB, IHC-P

Physical Properties

Liquid

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