Recombinant NKX2.2 Antibody [RMNK2-1]

Product Specifications

Background

NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity) . [UniProt]

NCBI Gene ID

4821

Swiss Prot

O95096

Host

Rabbit

Reactivity

Human

Immunogen

A human partial recombinant protein was used as the immunogen for this rabbit monoclonal NKX2.2 antibody.

Clonality

Recombinant Monoclonal

Clone

RMNK2-1

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

Protein A affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG, k

Applications Notes

1. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.