Recombinant TNF-alpha Antibody [RMTNFA-1]

Product Specifications

Background

The primary role of TNF is in the regulation of immune cells. TNFa, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1 & IL6 producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, Psoriasis and inflammatory bowel disease (IBD) . [Wiki]

NCBI Gene ID

7124

Swiss Prot

P01375

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the TNF-alpha antibody.

Clonality

Recombinant Monoclonal

Clone

RMTNFA-1

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology, Obesity, Signal Transduction

Purification

Protein A affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG, k

Applications Notes

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.

Symbol

TNF

NCBI Official Name

Tumor necrosis factor

NCBI Organism

Homo sapiens

Other Product Names

Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, TNF, TNFA, TNFSF2