Mucin-6 Antibody [MUCN6-1]
Product Specifications
Background
Mucin 6 may provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Highest expression seen in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. [UniProt]
NCBI Gene ID
4588
Swiss Prot
Q6W4X9
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the Mucin-6 antibody.
Clonality
Monoclonal
Clone
MUCN6-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-968
Fragment
IgG1, kappa
Specificity
Does not react with rat
Applications Notes
1. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
MUC6
NCBI Official Name
Mucin 6, oligomeric mucus/gel-forming
NCBI Organism
Homo sapiens
Tested Applications
IF, IHC-P
Physical Properties
Liquid
Curated Selection
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