Arginase 1 Antibody [T1ARG-1]
Product Specifications
Background
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [RefSeq]
NCBI Gene ID
383
Swiss Prot
P05089
Host
Mouse
Reactivity
Human
Immunogen
A C-terminal recombinant protein fragment from ARG1 was used as the immunogen for the Arginase 1 antibody.
Clonality
Monoclonal
Clone
T1ARG-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-951
Fragment
IgG3, kappa
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
ARG1
NCBI Official Name
Arginase 1
NCBI Organism
Homo sapiens
Other Product Names
Arginase-1, Liver-type arginase, Type I arginase, ARG1
Tested Applications
IF, WB, IHC-P
Physical Properties
Liquid
Curated Selection
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