MALT1 Antibody [4NMT-3]
Product Specifications
Background
Mucosa associated lymphoid tissue lymphoma translocation gene 1 is found in extranodal low-grade B cell lymphomas. It encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of the MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition.
NCBI Gene ID
10892
Swiss Prot
Q9UDY8
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment (aa 701-808) was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
4NMT-3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology
Purification
Protein G purified
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-934
Fragment
IgG1, kappa
Applications Notes
1. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
MALT1
NCBI Official Name
Mucosa associated lymphoid tissue lymphoma translocation gene 1
NCBI Organism
Homo sapiens
Other Product Names
Mucosa associated lymphoid tissue lymphoma translocation 1, IMD12, MLT, MLT1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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