PAX6 Antibody [PBPX6]
Product Specifications
Background
PAX6 is a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [RefSeq]
NCBI Gene ID
5080
Swiss Prot
P26367-2
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
A partial human PAX6 protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Clone
PBPX6
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction
Purification
Protein G purified antibody
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
PAX6
NCBI Official Name
Paired box 6
NCBI Organism
Homo sapiens
Other Product Names
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Tested Applications
WB
Physical Properties
Liquid
Frequently Asked Questions
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