FSH-beta Antibody [FLTPb-1]
Product Specifications
Background
Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
NCBI Gene ID
2488
Swiss Prot
P01225
Host
Mouse
Reactivity
Human
Immunogen
Recombinant hFSH beta subunit was used as the immunogen for the FSH-beta antibody. It does not cross-react with the alpha subunit
Clonality
Monoclonal
Clone
FLTPb-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
FSHB
NCBI Official Name
Follicle stimulating hormone, beta polypeptide
NCBI Organism
Homo sapiens
Other Product Names
Follitropin subunit beta, Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain, FSHB
Tested Applications
IF, IHC-P
Physical Properties
Liquid
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