CD6 Antibody [CLDA6-1]
Product Specifications
Background
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular “scavenger receptor cysteine-rich” (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. antibody to CD6 can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
NCBI Gene ID
923
Swiss Prot
P30203
Host
Mouse
Reactivity
Human
Immunogen
Human recombinant protein was used as the immunogen for this CD6 antibody.
Clonality
Monoclonal
Clone
CLDA6-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
CD6
NCBI Official Name
CD6 molecule
NCBI Organism
Homo sapiens
Other Product Names
CD6, CD6 molecule, T12, TP120, CD6 antigen
Tested Applications
Flow, IHC
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
