CD68 Antibody [LAM34-1]
Product Specifications
Background
CD68 plays a possible role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells. [UniProt]
NCBI Gene ID
968
Swiss Prot
P34810
Host
Mouse
Reactivity
Human
Immunogen
Purified CD68 protein was used as the immunogen for this CD68 antibody.
Clonality
Monoclonal
Clone
LAM34-1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, k
Applications Notes
1. FFPE testing requires sections to be boiled in pH6 10mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
CD68
NCBI Official Name
CD68 molecule
NCBI Organism
Homo sapiens
Other Product Names
Macrosialin, Gp110, CD68, CD68
Tested Applications
Flow, IF, IHC
Physical Properties
Liquid
Frequently Asked Questions
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