Transferrin Receptor (Extracellular domain) Antibody [TFRC/1817]
Product Specifications
Background
It recognizes a ~85-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This mAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
NCBI Gene ID
7037
Swiss Prot
P02786
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor / CD71 antibody.
Clonality
Monoclonal
Clone
TFRC/1817
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Obesity, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-824
Fragment
IgG2b, kappa
Symbol
TFRC
NCBI Official Name
Transferrin receptor
NCBI Organism
Homo sapiens
Other Product Names
Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, CD71, Transferrin receptor protein 1, serum form, sTfR, TFRC
Tested Applications
Flow, IF, IHC-P, ELISA, WB
Physical Properties
Liquid
Curated Selection
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