CDX2 Antibody [CDX2/1690]
Product Specifications
Background
The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
NCBI Gene ID
1045
Swiss Prot
Q99626
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 150-249 from the human protein were used as the immunogen for this CDX2 antibody.
Clonality
Monoclonal
Clone
CDX2/1690
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis, Stem Cell
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-767
Fragment
IgG2a, kappa
Symbol
CDX2
NCBI Official Name
Caudal type homeobox 2
NCBI Organism
Homo sapiens
Other Product Names
CDX2 Antibody: CDX3, CDX-3, CDX3, Homeobox protein CDX-2
Tested Applications
WB, IHC-P, Flow, IF
Physical Properties
Liquid
Curated Selection
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