SOX2 Antibody [SOX2/1791]
Product Specifications
Background
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.
NCBI Gene ID
6657
Swiss Prot
P48431
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.
Clonality
Monoclonal
Clone
SOX2/1791
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis, Stem Cell
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2b, kappa
Symbol
SOX2
NCBI Official Name
SRY (sex determining region Y) -box 2
NCBI Organism
Homo sapiens
Other Product Names
SOX2 Antibody: ANOP3, MCOPS3, Transcription factor SOX-2
Tested Applications
ELISA, WB, IHC-P
Physical Properties
Liquid
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