Growth Hormone Antibody [SPM106]
Product Specifications
Background
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly) .
NCBI Gene ID
2688
Swiss Prot
P01241
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 58-187 was used as the immunogen for this Growth Hormone antibody.
Clonality
Monoclonal
Clone
SPM106
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Cancer, Neuroscience
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2b
Symbol
Growth Hormone
NCBI Official Name
Growth hormone 1
NCBI Organism
Homo sapiens
Other Product Names
GH1, Growth hormone, GH, GHN, IGHD1B, GH-N, Pituitary growth hormone, Growth hormone 1, HGH-N, Somatotropin
Tested Applications
Flow, IHC-P, IF
Physical Properties
Liquid
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