MCM7 Antibody [SPM379]
Product Specifications
Background
MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
NCBI Gene ID
4176
Swiss Prot
P33993
Host
Mouse
Reactivity
Human
Immunogen
A human full length recombinant protein was used as the immunogen for the MCM7 antibody.
Clonality
Monoclonal
Clone
SPM379
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
MCM7
NCBI Official Name
Minichromosome maintenance complex component 7
NCBI Organism
Homo sapiens
Other Product Names
DNA replication licensing factor MCM7, CDC47 homolog, P11-MCM3, MCM7, CDC47, MCM2
Tested Applications
Flow, IF, IHC-P, WB
Physical Properties
Liquid
Frequently Asked Questions
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