NKX2.2 Antibody [NX2/1523]
Product Specifications
Background
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
NCBI Gene ID
4821
Swiss Prot
O95096
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody.
Clonality
Monoclonal
Clone
NX2/1523
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
NKX2-2
NCBI Official Name
NK2 homeobox 2
NCBI Organism
Homo sapiens
Other Product Names
NKX2-2 Antibody: NKX2B, NKX2.2, NKX2B, Homeobox protein NK-2 homolog B
Tested Applications
Flow, IHC-P, IF
Physical Properties
Liquid
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