FTL1 Antibody [FTL/1386]
Product Specifications
Background
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III) . Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
NCBI Gene ID
2512
Swiss Prot
P02792
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin Light Chain antibody.
Clonality
Monoclonal
Clone
FTL/1386
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2b
Symbol
FTL
NCBI Official Name
Ferritin, light polypeptide
NCBI Organism
Homo sapiens
Other Product Names
FTL, MGC71996, LFTD, NBIA3
Tested Applications
WB, Flow, IHC, IF
Physical Properties
Liquid
Curated Selection
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