Galectin 13 Antibody [PP13/1165]
Product Specifications
Background
It recognizes a 32kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13) . Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, LGALS13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, LGALS13 exists as a disulfide-linked homodimer. LGALS13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for LGALS13/Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.
NCBI Gene ID
29124
Swiss Prot
Q9UHV8
Host
Mouse
Reactivity
Human
Immunogen
A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the LGALS13 antibody.
Clonality
Monoclonal
Clone
PP13/1165
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-702
Fragment
IgG2b, kappa
Symbol
LGALS13
NCBI Official Name
Galectin 13
NCBI Organism
Homo sapiens
Tested Applications
WB, Flow, IF, ELISA, IHC-P
Physical Properties
Liquid
Curated Selection
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