INF39
INF39 is an irreversible and noncytotoxic NLRP3 inhibitor.
Product Specifications
CAS Number
[866028-26-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/INF39.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC)C(CC1=CC=CC=C1Cl)=C
Molecular Formula
C12H13ClO2
Molecular Weight
224.68
Precautions
H302, H315, H319, H335
References & Citations
[1]Cocco M, et al. Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.J Med Chem. 2017 May 11;60 (9) :3656-3671.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3
Available Sizes
Curated Selection
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