Clatherin Light Chain Antibody [SPM174]
Product Specifications
Background
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B) . Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
NCBI Gene ID
12111212
Swiss Prot
P09496, P09497
Host
Mouse
Reactivity
Human
Immunogen
A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.
Clonality
Monoclonal
Clone
SPM174
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2b, kappa
Symbol
CLTA, CLTB
NCBI Official Name
Clathrin light chain A, clathrin light chain B
NCBI Organism
Homo sapiens
Tested Applications
Flow, IF, WB, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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