Clatherin Light Chain Antibody [CLC/1421]
Product Specifications
Background
Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A & B) . Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
NCBI Gene ID
12111212
Swiss Prot
P09496, P09497
Host
Mouse
Reactivity
Human
Immunogen
A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.
Clonality
Monoclonal
Clone
CLC/1421
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-666
Fragment
IgG2b, kappa
Symbol
CLTA, CLTB
NCBI Official Name
Clathrin light chain A, clathrin light chain B
NCBI Organism
Homo sapiens
Tested Applications
Flow, IF, WB, IHC-P
Physical Properties
Liquid
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