CD44v6 Antibody [CD44v6/1246]

Product Specifications

Background

This antibody recognizes an epitope encoded by exon v6 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

NCBI Gene ID

960

Swiss Prot

P16070

Host

Mouse

Reactivity

Human

Immunogen

An amino acid sequence from the variant 6 domain of CD44 was used as the immunogen for the CD44v6 antibody.

Clonality

Monoclonal

Clone

CD44v6/1246

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction, Signal Transduction

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG2a, kappa

Symbol

CD44

NCBI Official Name

CD44 molecule (Indian blood group)

NCBI Organism

Homo sapiens

Other Product Names

CD44, CD44 molecule (Indian blood group), CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CD44 antigen, GP90 lymphocyte homing/adhesion receptor, Hermes antigen, cell surface glycoprotein CD44, chondroitin sulfate proteoglyc