Cadherin 16 Antibody
Product Specifications
Background
Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
NCBI Gene ID
1014
Swiss Prot
O75309
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein A affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG
Symbol
CDH16
NCBI Official Name
Cadherin 16, KSP-cadherin
NCBI Organism
Homo sapiens
Other Product Names
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Tested Applications
Flow, IF, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
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