AMACR / p504S Antibody [AMACR/1723]
Product Specifications
Background
AMACR, also known as p504S is an enzyme that is involved in bile acid biosynthesis and beta-oxidation of branched-chain fatty acids. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands.
NCBI Gene ID
23600
Swiss Prot
Q9UHK6
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human protein was used as the immunogen for the AMACR antibody.
Clonality
Monoclonal
Clone
AMACR/1723
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG
Symbol
AMACR
NCBI Official Name
Alpha-methylacyl-CoA racemase
NCBI Organism
Homo sapiens
Other Product Names
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Tested Applications
WB, IHC-P, IF
Physical Properties
Liquid
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