Gamma Catenin Antibody [CTNG/1483]
Product Specifications
Background
Plakoglobin is a major cytoplasmic component of both desmosomes and adherens junctions, and is the only known constituent common to submembranous plaques in both of these structures, which are located at the intercalated disc (ICD) of cardiomyocytes. It links cadherins to the actin cytoskeleton. Plakoglobin binds to conserved regions of desmoglein and desmocollin at intracellular catenin-binding sites to assemble desmosomes. [Wiki]
NCBI Gene ID
3728
Swiss Prot
P14923
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the Plakoglobin antibody.
Clonality
Monoclonal
Clone
CTNG/1483
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
JUP
NCBI Official Name
Junction plakoglobin
NCBI Organism
Homo sapiens
Other Product Names
Junction plakoglobin, Catenin gamma, Desmoplakin III, Desmoplakin-3, JUP, CTNNG, DP3
Tested Applications
IF, WB, Flow, IHC-P
Physical Properties
Liquid
Curated Selection
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