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SERPINA3 Antibody [AACT/1452]

Product Specifications

Background

Alpha 1-Antichymotrypsin, also called AACT and SERPINA3, inhibits the activity of certain proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving them into a different shape or conformation. This activity protects some tissues, such as the lower respiratory tract, from damage caused by proteolytic enzymes. This protein is produced in the liver, and is an acute phase protein that is induced during inflammation. [Wiki]

NCBI Gene ID

12

Swiss Prot

P01011

Host

Mouse

Reactivity

Human

Immunogen

A human partial recombinant protein was used as the immunogen for this Alpha-1-Antichymotrypsin antibody.

Clonality

Monoclonal

Clone

AACT/1452

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience

Purification

Protein G affinity

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG1

Symbol

SERPINA3

NCBI Official Name

Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3

NCBI Organism

Homo sapiens

Other Product Names

Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT

Tested Applications

WB, IHC-P, Flow, IF

Physical Properties

Liquid

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