TGFa Antibody [TGFA/1119]
Product Specifications
Background
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGFa is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
NCBI Gene ID
7039
Swiss Prot
P01135
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length TGF protein was used as the immunogen for the TGFa antibody.
Clonality
Monoclonal
Clone
TGFA/1119
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies, Antibody Pairs
Field of Research
Growth Factors
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
TGFA
NCBI Official Name
Transforming growth factor, alpha
NCBI Organism
Homo sapiens
Other Product Names
TFGAProtransforming growth factor alpha, EGF-like TGF, TGF-alpha
Tested Applications
Flow, IF, IHC-P
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
