ODC Antibody [ODC1/486]
Product Specifications
Background
Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
NCBI Gene ID
4953
Swiss Prot
P11926
Host
Mouse
Reactivity
Human, Rat
Immunogen
Recombinant human protein was used as the immunogen for the ODC antibody.
Clonality
Monoclonal
Clone
ODC1/486
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-450
Fragment
IgG2a, kappa
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
ODC1
NCBI Official Name
Ornithine decarboxylase
NCBI Organism
Homo sapiens
Other Product Names
Ornithine decarboxylase, ODC, ODC1
Tested Applications
Flow, IF, WB, IHC-P
Physical Properties
Liquid
Curated Selection
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