Interferon alpha Antibody [2.52]
Product Specifications
Background
This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
NCBI Gene ID
3439
Swiss Prot
P01562
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.
Clonality
Monoclonal
Clone
2.52
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Cancer
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-404
Fragment
IgG1, kappa
Symbol
IFNA1
NCBI Official Name
Interferon alpha 1
NCBI Organism
Homo sapiens
Tested Applications
WB, ELISA
Physical Properties
Liquid
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