CD57 Antibody [HNK-1 or Leu-7]

Product Specifications

Background

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

NCBI Gene ID

27087

Swiss Prot

Q9P2W7

Host

Mouse

Reactivity

Human

Immunogen

Human peripheral blood mononuclear cells were used as the immunogen for the CD57 antibody.

Clonality

Monoclonal

Clone

HNK-1 or Leu-7

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

PEG precipitation

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgM, kappa

Specificity

Does not react with rat

Applications Notes

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Symbol

B3GAT1

NCBI Official Name

Beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

NCBI Organism

Homo sapiens

Other Product Names

Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP