CD15 Antibody [FUT4/815]
Product Specifications
Background
CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
NCBI Gene ID
2526
Swiss Prot
P22083
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Purified human neutrophils were used as the immunogen for the CD15 antibody.
Clonality
Monoclonal
Clone
FUT4/815
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
PEG precipitation
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-366
Fragment
IgM, kappa
Applications Notes
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
FUT4
NCBI Official Name
Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
NCBI Organism
Homo sapiens
Other Product Names
Alpha- (1,3) -fucosyltransferase 4, 241-, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Fuc-TIV, FucT-IV, Galactoside 3-L-fucosyltransferase, FUT4, ELFT, FCT3A
Tested Applications
Flow, IF, IHC-P
Physical Properties
Liquid
Curated Selection
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