Semaphorin-4D Antibody [SEMA4D/933]
Product Specifications
Background
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
NCBI Gene ID
10507
Swiss Prot
Q92854
Host
Mouse
Reactivity
Human, Non-Human primate
Immunogen
Human recombinant protein was used as the immunogen for the Semaphorin-4D antibody.
Clonality
Monoclonal
Clone
SEMA4D/933
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-327
Fragment
IgG1, kappa
Symbol
SEMA4D
NCBI Official Name
Semaphorin 4D
NCBI Organism
Homo sapiens
Tested Applications
Flow, IF
Physical Properties
Liquid
Curated Selection
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