Semaphorin-4D Antibody [133-1C6]
Product Specifications
Background
Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026) . It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.
NCBI Gene ID
10507
Swiss Prot
Q92854
Host
Mouse
Reactivity
Human, Baboon
Immunogen
PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody.
Clonality
Monoclonal
Clone
133-1C6
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience
Purification
PEG precipitation
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-325
Fragment
IgM, kappa
Specificity
Does not react with Horse
Symbol
SEMA4D
NCBI Official Name
Semaphorin 4D
NCBI Organism
Homo sapiens
Tested Applications
Flow, IF
Physical Properties
Liquid
Curated Selection
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