CD45RO Antibody [190-2F2.5]
Product Specifications
Background
Recognizes a 180-185kDa protein, identified as isoform of leukocyte common antigen (CD45RO) . This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.
NCBI Gene ID
5788
Swiss Prot
P08575
Host
Mouse
Reactivity
Human
Immunogen
Lentillectin purified glycoproteins obtained from HuPBL and from a CLL (B cell) were used as immunogen for this CD45RO antibody.
Clonality
Monoclonal
Clone
190-2F2.5
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Neuroscience, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG2a, kappa
Symbol
PTPRC
NCBI Official Name
Protein tyrosine phosphatase, receptor type, C
NCBI Organism
Homo sapiens
Other Product Names
Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD45, PTPRC, CD45
Tested Applications
WB, Flow, IF
Physical Properties
Liquid
Frequently Asked Questions
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