CD19 Antibody [CVID3/429]
Product Specifications
Background
CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki]
NCBI Gene ID
930
Swiss Prot
P15391
Host
Mouse
Reactivity
Human, Monkey
Immunogen
Human CD19 recombinant protein was used as immunogen for this CD19 antibody.
Clonality
Monoclonal
Clone
CVID3/429
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
CD19
NCBI Official Name
CD19 molecule
NCBI Organism
Homo sapiens
Other Product Names
B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Differentiation antigen CD19, T-cell surface antigen Leu-12, CD19, CD19
Tested Applications
WB, Flow, IF
Physical Properties
Liquid
Frequently Asked Questions
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