HER-2 Antibody [ERB2/776]

Product Specifications

Background

ErbB2, also called HER2, is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. This ErbB2 antibody shows minimal cross-reaction with other members of the family. The protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

NCBI Gene ID

2064

Swiss Prot

P04626

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein (intracellular domain) was used as the immunogen for this HER-2 antibody. (2)

Clonality

Monoclonal

Clone

ERB2/776

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG1, kappa

Symbol

Her2

NCBI Official Name

Erb-b2 receptor tyrosine kinase 2

NCBI Organism

Homo sapiens

Other Product Names

ErbB-2 Antibody: NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19, HER-2/neu, MLN19, NEU, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein