ER Antibody [ER506]
Product Specifications
Background
Estrogen receptor (ER) is an important regulator of growth and differentiation in the mammary gland. ER presence in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. Clone ER506 antibody strongly stains nuclei of epithelial cells in breast carcinomas.
NCBI Gene ID
2099
Swiss Prot
P03372
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human ER alpha protein (aa 2-185) was used as the immunogen.
Clonality
Monoclonal
Clone
ER506
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Applications Notes
1. FFPE testing requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min and cooling at RT for 20 minutes.
Symbol
ESR1
NCBI Official Name
Estrogen receptor 1
NCBI Organism
Homo sapiens
Other Product Names
ESR1 Antibody: ER, ESR, Era, ESRA, ESTRR, NR3A1, Estrogen receptor, ER-alpha, ER
Tested Applications
WB, IHC, Flow
Physical Properties
Liquid
Curated Selection
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