CD2 Antibody [BH1]

Product Specifications

Background

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

NCBI Gene ID

914

Swiss Prot

P06729

Host

Mouse

Reactivity

Human

Immunogen

Human CD2 protein was used as the immunogen for this antibody.

Clonality

Monoclonal

Clone

BH1

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG2b, kappa

Symbol

CD2

NCBI Official Name

CD2 molecule

NCBI Organism

Homo sapiens

Other Product Names

CD2, CD2 antigen, Erythrocyte receptor, LFA-3 receptor, LFA-2, Lymphocyte-function antigen-2, T11, SRBC, CD2 molecule, Rosette receptor, T-cell surface antigen CD2