RUNX3 Antibody [RNX864]

Product Specifications

Background

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

NCBI Gene ID

864

Swiss Prot

Q13761

Host

Mouse

Reactivity

Human

Immunogen

A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.

Clonality

Monoclonal

Clone

RNX864

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Protein G Affinity Chromatography

Concentration

0.5 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

Fragment

IgG1, kappa

Symbol

RUNX3

NCBI Official Name

Runt-related transcription factor 3

NCBI Organism

Homo sapiens

Other Product Names

Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3