Cyclic GMP (sodium)
Product Specifications
Product Name Alternative
ALKS 8700; BIIB098
UNSPSC Description
Cyclic GMP sodium (cGMP) is an important regulator of short-term changes in smooth muscle tone and longer-term responses to chronic drug research or proliferative signals, it is in response to atrial natriuretic peptide (ANP) or nitric oxide (NO). Cyclic GMP sodium interacts with cation channels to regulate ion transport or activate the cyclic GMP-dependent protein kinase to result in protein phosphorylation[1][2].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cyclic-gmp-sodium.html
Purity
99.89
Solubility
H2O : 83.33 mg/mL (ultrasonic)
Smiles
O[C@@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O[C@@H]3CO4)[C@@H]3OP4([O-])=O.[Na+]
Molecular Weight
367.19
References & Citations
[1]Rybalkin SD, et al. Cyclic GMP phosphodiesterases and regulation of smooth muscle function. Circ Res. 2003 Aug 22;93(4):280-91.|[2]Murad F. Shattuck Lecture. Nitric oxide and cyclic GMP in cell signaling and drug development. N Engl J Med. 2006 Nov 9;355(19):2003-11. doi: 10.1056/NEJMsa063904. PMID: 17093251.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113469A/Cyclic-GMP-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113469A/Cyclic-GMP-sodium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
40732-48-7
Available Sizes
Curated Selection
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