Viperin Antibody
Product Specifications
Background
Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs) .
NCBI Gene ID
91543
Swiss Prot
Q8WXG1
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein A affinity chromatography purified antibody
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=33-037
Fragment
IgG
Symbol
RSAD2
NCBI Official Name
Radical S-adenosyl methionine domain containing 2
NCBI Organism
Homo sapiens
Other Product Names
RSAD2, 2510004L01Rik, cig33, cig5, vig1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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