SGK1 Antibody
Product Specifications
Background
SGK1 (Serine/threonine-protein kinase 1) is a member of a serine/threonine subfamily of kinases. This kinase is involved in a wide variety of cellular functions including cell growth, survival and migration as well as a wide variety of cellular processes including transcription (Foxo3A, b-catenin, NF-kB, and p53), stress response and apoptosis. SGK1 also participates in neuronal function. Expression of SGK1 is stimulated by amphetamine, LSD and neuronal injury, it stimulates dendrite growth, is important in long term memory, fear-conditioning/spatial/novel object recognition learning and is likely involved in the pathophysiology of Alzheimer's disease.
NCBI Gene ID
6446
Swiss Prot
O00141
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminal region of human SGK1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein A affinity chromatography
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Fragment
IgG
Symbol
SGK1
NCBI Official Name
Serum/glucocorticoid regulated kinase 1
NCBI Organism
Homo sapiens
Other Product Names
SGK1 Antibody: SGK, SGK
Tested Applications
WB
Physical Properties
Liquid
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