RAX Antibody
Product Specifications
Background
Rax (Retinal and anterior neural fold homeobox), a paired-type homeobox protein, is a human homolog of Drosophila Rx protein. It is a marker of developing eye and forebrain in vertebrates, initially expressed in the region of the forebrain where optic vesicles are formed, and is involved in promoting the division of retinal progenitor cells early in development. As development progresses, expression is seen in the retina and hypothalamus. RAX is essential for eye development. Knockout of RAX in mice eliminated eye development, and RAX mutation in humans result in Anophthalmia, where one or both eyes fail to develop.
NCBI Gene ID
30062
Swiss Prot
Q9Y2V3
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminus of human RAX was used as the immunogen for this antibody.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Protein A affinity chromatography
Concentration
0.5 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Fragment
IgG
Symbol
RAX
NCBI Official Name
Retina and anterior neural fold homeobox
NCBI Organism
Homo sapiens
Other Product Names
Retinal homeobox protein Rx, Retina and anterior neural fold homeobox protein, RAX, RX
Tested Applications
WB
Physical Properties
Liquid
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