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Als2Cr2 Antibody

Product Specifications

Background

Als2Cr2, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, is a serine/threonine protein kinase encoded by the STRADB gene, discovered as an XIAP interacting protein. It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases. Alone, it only moderately activates JNKs, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, protecting against Caspase 1- or Fas-induced apoptosis.

NCBI Gene ID

55437

Swiss Prot

Q9C0K7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis

Purification

Protein A affinity chromatography

Concentration

0.5 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

Fragment

IgG

Symbol

STRADB

NCBI Official Name

STE20-related kinase adaptor beta

NCBI Organism

Homo sapiens

Other Product Names

ILPIP Antibody: PAPK, ILPIP, ILPIPA, ALS2CR2, CALS-21, PRO1038, STE20-related kinase adapter protein beta, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein, STRAD beta

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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