WFDC12 Antibody

Product Specifications

Background

This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.

NCBI Gene ID

128488

Swiss Prot

Q8WWY7

Accession Number

Q8WWY7

Host

Rabbit

Reactivity

Human

Immunogen

This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human WFDC12.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

12 kDa

Fragment

Rabbit Ig

Symbol

WFDC12

NCBI Official Name

WAP four-disulfide core domain protein 12

NCBI Organism

Homo sapiens

Background Reference 01

Clauss, A., et al. Biochem. Biophys. Res. Commun. 333 (2) :383-389 (2005)

Background Reference 02

Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)

Background Reference 03

Clauss, A., et al. Biochem. J. 368 (PT 1), 233-242 (2002) :

Background Reference 04

Lundwall, A., et al. Biochem. Biophys. Res. Commun. 290 (1) :452-456 (2002)

Other Product Names

WAP four-disulfide core domain protein 12, Putative protease inhibitor WAP12, Whey acidic protein 2, WFDC12, C20orf122, WAP2

Tested Applications

WB, IHC-P, Flow

Protein ID

24212610

Physical Properties

Liquid

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