FBXW12 Antibody
Product Specifications
Background
Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]) .[supplied by OMIM].
NCBI Gene ID
285231
Swiss Prot
Q6X9E4
Accession Number
Q6X9E4
Host
Rabbit
Reactivity
Human
Immunogen
This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-114
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
FBXW12
NCBI Official Name
F-box/WD repeat-containing protein 12
NCBI Organism
Homo sapiens
Background Reference 01
Jin, J., et al. Genes Dev. 18 (21) :2573-2580 (2004)
Background Reference 02
Zeng, L., et al. Mol. Biol. Rep. 31 (1) :51-57 (2004)
Other Product Names
F-box/WD repeat-containing protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, FBXW12, FBW12, FBXO12, FBXO35
Tested Applications
WB, IHC-P, Flow
Protein ID
215273983
Physical Properties
Liquid
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