PEMT Antibody
Product Specifications
Background
PEMT is an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17.
NCBI Gene ID
10400
Swiss Prot
Q9UBM1
Accession Number
Q9UBM1
Host
Rabbit
Reactivity
Human
Immunogen
This PEMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the C-terminal region of human PEMT.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PEMT
NCBI Official Name
Phosphatidylethanolamine N-methyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Walkey C.J., Biochim. Biophys. Acta 1436:405-412 (1999) .
Background Reference 02
Shields D.J., Biochim. Biophys. Acta 1532:105-114 (2001) .
Background Reference 03
Hu R.-M., Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548 (2000) .
Other Product Names
Phosphatidylethanolamine N-methyltransferase, PEAMT, PEMT, PEMT2, PEMT, PEMPT, PNMT
Tested Applications
WB
Protein ID
148887406
Physical Properties
Liquid
Curated Selection
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