L2HGDH Antibody

Product Specifications

Background

This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.

NCBI Gene ID

79944

Swiss Prot

Q9H9P8

Accession Number

Q9H9P8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

L2HGDH

NCBI Official Name

L-2-hydroxyglutarate dehydrogenase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Short, A.D., et al. Vet. Rec. 167 (12) :455-457 (2010)

Background Reference 02

Steenweg, M.E., et al. Hum. Mutat. 31 (4) :380-390 (2010)

Background Reference 03

Kranendijk, M., et al. Hum. Mutat. 31 (3) :279-283 (2010)

Background Reference 04

Vilarinho, L., et al. J. Hum. Genet. 55 (1) :55-58 (2010)

Other Product Names

L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, L2HGDH, C14orf160

Tested Applications

Protein ID

317373422

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

abx506677 96 Tests

Human Carbohydrate sulfotransferase 6 (CHST6) ELISA Kit

Ask

View Details

sc-268450 10 mg

8-Methoxy-2,3,4,5-tetrahydro-benzo[c]azepin-1-one

Ask

View Details

sc-149763 10 µM

Myosin VIIB siRNA (m)

Ask

View Details

abx321472-01 20 µL

Caspase 6 (CASP6) Antibody

Ask

View Details

abx321472-02 50 µL

Caspase 6 (CASP6) Antibody

Ask

View Details

abx321472-03 100 µL

Caspase 6 (CASP6) Antibody

Ask

View Details