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FGF9 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.

NCBI Gene ID

2254

Swiss Prot

P31371

Accession Number

P31371

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This FGF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-58 amino acids from the N-terminal region of human FGF9.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

FGF9

NCBI Official Name

Fibroblast growth factor 9

NCBI Organism

Homo sapiens

Background Reference 01

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 02

Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :

Background Reference 03

Kalinina, J., et al. Mol. Cell. Biol. 29 (17) :4663-4678 (2009)

Background Reference 04

Marroni, F., et al. Circ Cardiovasc Genet 2 (4) :322-328 (2009)

Other Product Names

Fibroblast growth factor 9, FGF-9, Glia-activating factor, GAF, Heparin-binding growth factor 9, HBGF-9, FGF9

Tested Applications

WB, Flow

Protein ID

544290

Physical Properties

Liquid

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